Publications

Found 163 results
Filters: Author is S Muyldermans  [Clear All Filters]
2008
Saerens, D., G. Hassanzade Ghassabeh, and S. Muyldermans, "Antibody technology in proteomics.", Brief Funct Genomic Proteomic, vol. 7, issue 4, pp. 275-82, 2008 Jul.
Saerens, D., K. Conrath, J. Govaert, and S. Muyldermans, "Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.", J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
Saerens, D., B. Stijlemans, T. Nath Baral, G. Thanh Nguy Thi, U. Wernery, S. Magez, P. De Baetselier, S. Muyldermans, and K. Conrath, "Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.", J Immunol Methods, vol. 329, issue 1-2, pp. 138-50, 2008 Jan 1.
Saerens, D., G. Hassanzade Ghassabeh, and S. Muyldermans, "Single-domain antibodies as building blocks for novel therapeutics.", Curr Opin Pharmacol, vol. 8, issue 5, pp. 600-8, 2008 Oct.
Rothbauer, U., K. Zolghadr, S. Muyldermans, A. Schepers, C. M Cardoso, and H. Leonhardt, "A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins.", Mol Cell Proteomics, vol. 7, issue 2, pp. 282-9, 2008 Feb.
Hmila, I., B. Abderrazek R, D. Saerens, Z. Benlasfar, K. Conrath, M. El Ayeb, S. Muyldermans, and B. Bouhaouala-Zahar, "VHH, bivalent domains and chimeric Heavy chain-only antibodies with high neutralizing efficacy for scorpion toxin AahI'.", Mol Immunol, vol. 45, issue 14, pp. 3847-56, 2008 Aug.
2006
De Genst, E., D. Saerens, S. Muyldermans, and K. Conrath, "Antibody repertoire development in camelids.", Dev Comp Immunol, vol. 30, issue 1-2, pp. 187-98, 2006.
Kacskovics, I., B. Mayer, Z. Kis, L. V. Frenyó, Y. Zhao, S. Muyldermans, and L. Hammarström, "Cloning and characterization of the dromedary (Camelus dromedarius) neonatal Fc receptor (drFcRn).", Dev Comp Immunol, vol. 30, issue 12, pp. 1203-15, 2006.
Baral, T. Nath, S. Magez, B. Stijlemans, K. Conrath, B. Vanhollebeke, E. Pays, S. Muyldermans, and P. De Baetselier, "[Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor].", Med Sci (Paris), vol. 22, issue 11, pp. 914-6, 2006 Nov.
Baral, T. Nath, S. Magez, B. Stijlemans, K. Conrath, B. Vanhollebeke, E. Pays, S. Muyldermans, and P. De Baetselier, "Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor.", Nat Med, vol. 12, issue 5, pp. 580-4, 2006 May.
Brüggemann, M., J. A. Smith, M. J. Osborn, D. Corcos, X. Zou, V. Khong Nguyen, and S. Muyldermans, "Heavy-chain-only antibody expression and B-cell development in the mouse.", Crit Rev Immunol, vol. 26, issue 5, pp. 377-90, 2006.
De Genst, E., K. Silence, K. Decanniere, K. Conrath, R. Loris, J. Kinne, S. Muyldermans, and L. Wyns, "Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.", Proc Natl Acad Sci U S A, vol. 103, issue 12, pp. 4586-91, 2006 Mar 21.
Marquardt, A., S. Muyldermans, and M. Przybylski, "A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry.", Chemistry, vol. 12, issue 7, pp. 1915-23, 2006 Feb 20.
Rothbauer, U., K. Zolghadr, S. Tillib, D. Nowak, L. Schermelleh, A. Gahl, N. Backmann, K. Conrath, S. Muyldermans, C. M Cardoso, et al., "Targeting and tracing antigens in live cells with fluorescent nanobodies.", Nat Methods, vol. 3, issue 11, pp. 887-9, 2006 Nov.
2005
Conrath, K., C. Vincke, B. Stijlemans, J. Schymkowitz, K. Decanniere, L. Wyns, S. Muyldermans, and R. Loris, "Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.", J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
Saerens, D., F. Frederix, G. Reekmans, K. Conrath, K. Jans, L. Brys, L. Huang, E. Bosmans, G. Maes, G. Borghs, et al., "Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing.", Anal Chem, vol. 77, issue 23, pp. 7547-55, 2005 Dec 1.
Zou, X., J. A. Smith, V. Khong Nguyen, L. Ren, K. Luyten, S. Muyldermans, and M. Brüggemann, "Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.", J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Revets, H., P. De Baetselier, and S. Muyldermans, "Nanobodies as novel agents for cancer therapy.", Expert Opin Biol Ther, vol. 5, issue 1, pp. 111-24, 2005 Jan.
Huang, L., G. Reekmans, D. Saerens, J-M. Friedt, F. Frederix, L. Francis, S. Muyldermans, A. Campitelli, and C. Van Hoof, "Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays.", Biosens Bioelectron, vol. 21, issue 3, pp. 483-90, 2005 Sep 15.
Dumoulin, M., D. Canet, A. M. Last, E. Pardon, D. B. Archer, S. Muyldermans, L. Wyns, A. Matagne, C. V. Robinson, C. Redfield, et al., "Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.", J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
De Genst, E., K. Silence, M. Arbabi Ghahroudi, K. Decanniere, R. Loris, J. Kinne, L. Wyns, and S. Muyldermans, "Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.", J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.

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