Publications

Found 199 results
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2010
Abskharon, R. N. N., S. H. Soror, E. Pardon, H. El Hassan, G. Legname, J. Steyaert, and A. Wohlkonig, "Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 66, issue Pt 12, pp. 1644-6, 2010 Dec 1.
Chorell, E., J. S. Pinkner, G. Phan, S. Edvinsson, F. Buelens, H. Remaut, G. Waksman, S. J. Hultgren, and F. Almqvist, "Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity.", J Med Chem, vol. 53, issue 15, pp. 5690-5, 2010 Aug 12.
Remans, K., K. Pauwels, P. van Ulsen, L. Buts, P. Cornelis, J. Tommassen, S. N. Savvides, K. Decanniere, and P. Van Gelder, "Hydrophobic surface patches on LolA of Pseudomonas aeruginosa are essential for lipoprotein binding.", J Mol Biol, vol. 401, issue 5, pp. 921-30, 2010 Sep 3.
Van den Abbeele, A., S. De Clercq, A. De Ganck, V. De Corte, B. Van Loo, S. Hamdy Soror, V. Srinivasan, J. Steyaert, J. Vandekerckhove, and J. Gettemans, "A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction.", Cell Mol Life Sci, vol. 67, issue 9, pp. 1519-35, 2010 May.
Vandemeulebroucke, A., C. Minici, I. Bruno, L. Muzzolini, P. Tornaghi, D. W. Parkin, W. Versées, J. Steyaert, and M. Degano, "Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.", Biochemistry, vol. 49, issue 41, pp. 8999-9010, 2010 Oct 19.
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
Vercheval, L., C. Bauvois, A. di Paolo, F. Borel, J-L. Ferrer, E. Sauvage, A. Matagne, J-M. Frère, P. Charlier, M. Galleni, et al., "Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70.", Biochem J, vol. 432, issue 3, pp. 495-504, 2010 Dec 15.
2009
Conrath, K., A. S. Pereira, C. E. Martins, C. G. Timóteo, P. Tavares, S. Spinelli, J. Kinne, C. Flaudrops, C. Cambillau, S. Muyldermans, et al., "Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.", Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
Garcia-Pino, A., S. Martinez-Rodriguez, K. Wahni, L. Wyns, R. Loris, and J. Messens, "Coupling of domain swapping to kinetic stability in a thioredoxin mutant.", J Mol Biol, vol. 385, issue 5, pp. 1590-9, 2009 Feb 6.
Baurin, S., L. Vercheval, F. Bouillenne, C. Falzone, A. Brans, L. Jacquamet, J-L. Ferrer, E. Sauvage, D. Dehareng, J-M. Frère, et al., "Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.", Biochemistry, vol. 48, issue 47, pp. 11252-63, 2009 Dec 1.
Korotkov, K. V., E. Pardon, J. Steyaert, and W. G. J. Hol, "Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.", Structure, vol. 17, issue 2, pp. 255-65, 2009 Feb 13.
Versées, W., A. Goeminne, M. Berg, A. Vandemeulebroucke, A. Haemers, K. Augustyns, and J. Steyaert, "Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.", Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.
Beck, J., L. Vercheval, C. Bebrone, A. Herteg-Fernea, P. Lassaux, and J. Marchand-Brynaert, "Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate.", Bioorg Med Chem Lett, vol. 19, issue 13, pp. 3593-7, 2009 Jul 1.
Van Molle, I., K. Moonens, L. Buts, A. Garcia-Pino, S. Panjikar, L. Wyns, H. De Greve, and J. Bouckaert, "The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces.", Acta Crystallogr D Biol Crystallogr, vol. 65, issue Pt 5, pp. 411-20, 2009 May.
Vincke, C., R. Loris, D. Saerens, S. Martinez-Rodriguez, S. Muyldermans, and K. Conrath, "General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.", J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
Lam, A. Y., E. Pardon, K. V. Korotkov, W. G. J. Hol, and J. Steyaert, "Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.", J Struct Biol, vol. 166, issue 1, pp. 8-15, 2009 Apr.
De Jonge, N., A. Garcia-Pino, L. Buts, S. Haesaerts, D. Charlier, K. Zangger, L. Wyns, H. De Greve, and R. Loris, "Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain.", Mol Cell, vol. 35, issue 2, pp. 154-63, 2009 Jul 31.
2008
Meyer, S., A. Scrima, W. Versées, and A. Wittinghofer, "Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate.", J Mol Biol, vol. 380, issue 3, pp. 532-47, 2008 Jul 11.
Martinez-Rodriguez, S., A. Garcia-Pino, F. Javier Las Heras-Vázquez, J. María Clemente-Jiménez, F. Rodríguez-Vico, R. Loris, J. Ma García-Ruiz, and J. Antonio Gavira, "Crystallization and preliminary crystallographic studies of the recombinant L-N-carbamoylase from Geobacillus stearothermophilus CECT43.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 64, issue Pt 12, pp. 1135-8, 2008 Dec 1.
Remaut, H., C. Tang, N. S. Henderson, J. S. Pinkner, T. Wang, S. J. Hultgren, D. G. Thanassi, G. Waksman, and H. Li, "Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.", Cell, vol. 133, issue 4, pp. 640-52, 2008 May 16.
Wellens, A., C. Garofalo, H. Nguyen, N. Van Gerven, R. Slättegård, J-P. Hernalsteens, L. Wyns, S. Oscarson, H. De Greve, S. Hultgren, et al., "Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.", PLoS One, vol. 3, issue 4, pp. e2040, 2008.
Kiss, R., D. Kovacs, P. Tompa, and A. Perczel, "Local structural preferences of calpastatin, the intrinsically unstructured protein inhibitor of calpain.", Biochemistry, vol. 47, issue 26, pp. 6936-45, 2008 Jul 1.
Rodriguez, S. Martinez, S. Panjikar, K. Van Belle, L. Wyns, J. Messens, and R. Loris, "Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli.", Protein Sci, vol. 17, issue 4, pp. 681-90, 2008 Apr.
Dosztányi, Z., and P. Tompa, "Prediction of protein disorder.", Methods Mol Biol, vol. 426, pp. 103-15, 2008.
Kardos, J., V. Harmat, A. Palló, O. Barabás, K. Szilágyi, L. Gráf, G. Náray-Szabó, Y. Goto, P. Závodszky, and P. Gál, "Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.", Mol Immunol, vol. 45, issue 6, pp. 1752-60, 2008 Mar.

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