Publications

Found 310 results
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2014
Glennon, J., D. Purper-Ouakil, M. Bakker, A. Zuddas, P. Hoekstra, U. Schulze, J. Castro-Fornieles, P. J. Santosh, C. Arango, M. Kölch, et al., "Paediatric European Risperidone Studies (PERS): context, rationale, objectives, strategy, and challenges.", Eur Child Adolesc Psychiatry, vol. 23, issue 12, pp. 1149-60, 2014 Dec.
Tompa, P., and M. Varadi, "Predicting the predictive power of IDP ensembles.", Structure, vol. 22, issue 2, pp. 177-8, 2014 Feb 04.
Abskharon, R. N. N., G. Giachin, A. Wohlkonig, S. H. Soror, E. Pardon, G. Legname, and J. Steyaert, "Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody.", J Am Chem Soc, vol. 136, issue 3, pp. 937-44, 2014 Jan 22.
Triest, S., A. Wohlkonig, E. Pardon, and J. Steyaert, "Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody.", Acta Crystallogr F Struct Biol Commun, vol. 70, issue Pt 11, pp. 1504-7, 2014 Nov.
Staus, D. P., L. M. Wingler, R. T. Strachan, S. G. F. Rasmussen, E. Pardon, S. Ahn, J. Steyaert, B. K. Kobilka, and R. J. Lefkowitz, "Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies.", Mol Pharmacol, vol. 85, issue 3, pp. 472-81, 2014 Mar.
Sterckx, Y. G. J., A. Volkov, W. F. Vranken, J. Kragelj, M. Ringkjøbi Jensen, L. Buts, A. Garcia-Pino, T. Jové, L. Van Melderen, M. Blackledge, et al., "Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2.", Structure, vol. 22, issue 6, pp. 854-65, 2014 Jun 10.
Chaikuad, A., T. Keates, C. Vincke, M. Kaufholz, M. Zenn, B. Zimmermann, C. Gutiérrez, R-G. Zhang, C. Hatzos-Skintges, A. Joachimiak, et al., "Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.", Biochem J, vol. 459, issue 1, pp. 59-69, 2014 Apr 1.
M Ceregido, A., M. Spínola Amilibia, L. Buts, J. Rivera-Torres, A. Garcia-Pino, J. Bravo, and N. A. J. van Nuland, "The structure of TAX1BP1 UBZ1+2 provides insight into target specificity and adaptability.", J Mol Biol, vol. 426, issue 3, pp. 674-90, 2014 Feb 06.
Lo, A. W. H., K. Van de Water, P. J. Gane, A. W. Edith Chan, D. Steadman, K. Stevens, D. L. Selwood, G. Waksman, and H. Remaut, "Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization.", J Antimicrob Chemother, vol. 69, issue 4, pp. 1017-26, 2014 Apr.
Macossay-Castillo, M., S. Kosol, P. Tompa, and R. Pancsa, "Synonymous constraint elements show a tendency to encode intrinsically disordered protein segments.", PLoS Comput Biol, vol. 10, issue 5, pp. e1003607, 2014 May.
Hubin, E., N. A. J. van Nuland, K. Broersen, and K. Pauwels, "Transient dynamics of Aβ contribute to toxicity in Alzheimer's disease.", Cell Mol Life Sci, vol. 71, issue 18, pp. 3507-21, 2014 Sep.
Ditlev, S. B., R. Florea, M. A. Nielsen, T. G. Theander, S. Magez, P. Boeuf, and A. Salanti, "Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.", PLoS One, vol. 9, issue 1, pp. e84981, 2014.
2013
Kruse, A. C., A. M. Ring, A. Manglik, J. Hu, K. Hu, K. Eitel, H. Hübner, E. Pardon, C. Valant, P. M. Sexton, et al., "Activation and allosteric modulation of a muscarinic acetylcholine receptor.", Nature, vol. 504, issue 7478, pp. 101-6, 2013 Dec 05.
De Vos, J., N. Devoogdt, T. Lahoutte, and S. Muyldermans, "Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target.", Expert Opin Biol Ther, vol. 13, issue 8, pp. 1149-60, 2013 Aug.
Dubovskii, P. V., A. G. Konshina, and R. G. Efremov, "Cobra cardiotoxins: membrane interactions and pharmacological potential.", Curr Med Chem, vol. 21, issue 3, pp. 270-87, 2013.
Irannejad, R., J. C. Tomshine, J. R. Tomshine, M. Chevalier, J. P. Mahoney, J. Steyaert, S. G. F. Rasmussen, R. K. Sunahara, H. El-Samad, B. Huang, et al., "Conformational biosensors reveal GPCR signalling from endosomes.", Nature, vol. 495, issue 7442, pp. 534-8, 2013 Mar 28.
Behdani, M., S. Zeinali, M. Karimipour, H. Khanahmad, S. Schoonooghe, A. Aslemarz, N. Seyed, R. Moazami-Godarzi, F. Baniahmad, M. Habibi-Anbouhi, et al., "Development of VEGFR2-specific Nanobody Pseudomonas exotoxin A conjugated to provide efficient inhibition of tumor cell growth.", N Biotechnol, vol. 30, issue 2, pp. 205-9, 2013 Jan 25.
Arts, I. S., G. Ball, P. Leverrier, S. Garvis, V. Nicolaes, D. Vertommen, B. Ize, V. Tamu Dufe, J. Messens, R. Voulhoux, et al., "Dissecting the machinery that introduces disulfide bonds in Pseudomonas aeruginosa.", MBio, vol. 4, issue 6, pp. e00912-13, 2013 Dec 10.
Lensink, M. F., and S. J. Wodak, "Docking, scoring, and affinity prediction in CAPRI.", Proteins, vol. 81, issue 12, pp. 2082-95, 2013 Dec.
Schad, E., L. Kalmar, and P. Tompa, "Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome.", Nucleic Acids Res, vol. 41, issue 8, pp. 4409-22, 2013 Apr.
Cilia, E., R. Pancsa, P. Tompa, T. Lenaerts, and W. F. Vranken, "From protein sequence to dynamics and disorder with DynaMine.", Nat Commun, vol. 4, pp. 2741, 2013.
Sazanov, L. A., R. Baradaran, R. G. Efremov, J. M. Berrisford, and G. Minhas, "A long road towards the structure of respiratory complex I, a giant molecular proton pump.", Biochem Soc Trans, vol. 41, issue 5, pp. 1265-71, 2013 Oct.
Vercruysse, T., E. Boons, T. Venken, E. Vanstreels, A. Voet, J. Steyaert, M. De Maeyer, and D. Daelemans, "Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev.", PLoS One, vol. 8, issue 4, pp. e60259, 2013.
Banner, D. W., B. Gsell, J. Benz, J. Bertschinger, D. Burger, S. Brack, S. Cuppuleri, M. Debulpaep, A. Gast, D. Grabulovski, et al., "Mapping the conformational space accessible to BACE2 using surface mutants and cocrystals with Fab fragments, Fynomers and Xaperones.", Acta Crystallogr D Biol Crystallogr, vol. 69, issue Pt 6, pp. 1124-37, 2013 Jun.
Guerry, P., L. Salmon, L. Mollica, J. L. Ortega Roldan, P. Markwick, N. A. J. van Nuland, A. J McCammon, and M. Blackledge, "Mapping the population of protein conformational energy sub-states from NMR dipolar couplings.", Angew Chem Int Ed Engl, vol. 52, issue 11, pp. 3181-5, 2013 Mar 11.

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