Publications

Found 33 results

Filters: Keyword is Binding Sites and Author is Jan Steyaert [Clear All Filters]

1998

Zegers, I., R. Loris, G. Dehollander, F. A Haikal, F. Poortmans, J. Steyaert, and L. Wyns, "Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.", Nat Struct Biol, vol. 5, issue 4, pp. 280-3, 1998 Apr.

1995

Steyaert, J., and Y. Engelborghs, "A two-binding-site kinetic model for the ribonuclease-T1-catalysed transesterification of dinucleoside phosphate substrates.", Eur J Biochem, vol. 233, issue 1, pp. 140-4, 1995 Oct 1.

1994

Pletinckx, J., J. Steyaert, I. Zegers, H. W. Choe, U. Heinemann, and L. Wyns, "Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution.", Biochemistry, vol. 33, issue 7, pp. 1654-62, 1994 Feb 22.

Steyaert, J., A. F. Haikal, and L. Wyns, "Investigation of the functional interplay between the primary site and the subsite of RNase T1: kinetic analysis of single and multiple mutants for modified substrates.", Proteins, vol. 18, issue 4, pp. 318-23, 1994 Apr.

1992

Zegers, I., P. Verhelst, H. W. Choe, J. Steyaert, U. Heinemann, W. Saenger, and L. Wyns, "Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.", Biochemistry, vol. 31, issue 46, pp. 11317-25, 1992 Nov 24.

1991

Steyaert, J., C. Opsomer, L. Wyns, and P. Stanssens, "Quantitative analysis of the contribution of Glu46 and Asn98 to the guanosine specificity of ribonuclease T1.", Biochemistry, vol. 30, issue 2, pp. 494-9, 1991 Jan 15.

Steyaert, J., A. F. Haikal, L. Wyns, and P. Stanssens, "Subsite interactions of ribonuclease T1: Asn36 and Asn98 accelerate GpN transesterification through interactions with the leaving nucleoside N.", Biochemistry, vol. 30, issue 35, pp. 8666-70, 1991 Sep 3.

Steyaert, J., L. Wyns, and P. Stanssens, "Subsite interactions of ribonuclease T1: viscosity effects indicate that the rate-limiting step of GpN transesterification depends on the nature of N.", Biochemistry, vol. 30, issue 35, pp. 8661-5, 1991 Sep 3.

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