Publications
Found 171 results
Filters: Author is Muyldermans, Serge [Clear All Filters]
"Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.",
J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
"Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing.",
Anal Chem, vol. 77, issue 23, pp. 7547-55, 2005 Dec 1.
"Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.",
J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Nanobodies as novel agents for cancer therapy.",
Expert Opin Biol Ther, vol. 5, issue 1, pp. 111-24, 2005 Jan.
"Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays.",
Biosens Bioelectron, vol. 21, issue 3, pp. 483-90, 2005 Sep 15.
"Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.",
J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Chemical basis for the affinity maturation of a camel single domain antibody.",
J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
"Efficient cancer therapy with a nanobody-based conjugate.",
Cancer Res, vol. 64, issue 8, pp. 2853-7, 2004 Apr 15.
"Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.",
J Biol Chem, vol. 279, issue 2, pp. 1256-61, 2004 Jan 9.
"Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.",
J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.
"An S-layer heavy chain camel antibody fusion protein for generation of a nanopatterned sensing layer to detect the prostate-specific antigen by surface plasmon resonance technology.",
Bioconjug Chem, vol. 15, issue 3, pp. 664-71, 2004 May-Jun.
"A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.",
Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
"Crystal structure of the intrinsically flexible addiction antidote MazE.",
J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.
"Emergence and evolution of functional heavy-chain antibodies in Camelidae.",
Dev Comp Immunol, vol. 27, issue 2, pp. 87-103, 2003 Feb.
"Generation of a functional monomolecular protein lattice consisting of an s-layer fusion protein comprising the variable domain of a camel heavy chain antibody.",
Bioconjug Chem, vol. 14, issue 2, pp. 440-8, 2003 Mar-Apr.
"Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells.",
Immunology, vol. 109, issue 1, pp. 93-101, 2003 May.
"Efficient tumor targeting by single-domain antibody fragments of camels.",
Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
"Heavy-chain antibodies in Camelidae; a case of evolutionary innovation.",
Immunogenetics, vol. 54, issue 1, pp. 39-47, 2002 Apr.
"Kinetic and affinity predictions of a protein-protein interaction using multivariate experimental design.",
J Biol Chem, vol. 277, issue 33, pp. 29897-907, 2002 Aug 16.
"Single-domain antibody fragments with high conformational stability.",
Protein Sci, vol. 11, issue 3, pp. 500-15, 2002 Mar.
"Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.",
J Biol Chem, vol. 277, issue 26, pp. 23645-50, 2002 Jun 28.
"Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody.",
J Biol Chem, vol. 276, issue 28, pp. 26285-90, 2001 Jul 13.
"Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae.",
Antimicrob Agents Chemother, vol. 45, issue 10, pp. 2807-12, 2001 Oct.