Publications

Found 171 results
Filters: Author is Muyldermans, Serge  [Clear All Filters]
2005
Conrath, K., C. Vincke, B. Stijlemans, J. Schymkowitz, K. Decanniere, L. Wyns, S. Muyldermans, and R. Loris, "Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.", J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
Saerens, D., F. Frederix, G. Reekmans, K. Conrath, K. Jans, L. Brys, L. Huang, E. Bosmans, G. Maes, G. Borghs, et al., "Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing.", Anal Chem, vol. 77, issue 23, pp. 7547-55, 2005 Dec 1.
Zou, X., J. A. Smith, V. Khong Nguyen, L. Ren, K. Luyten, S. Muyldermans, and M. Brüggemann, "Expression of a dromedary heavy chain-only antibody and B cell development in the mouse.", J Immunol, vol. 175, issue 6, pp. 3769-79, 2005 Sep 15.
Saerens, D., M. Pellis, R. Loris, E. Pardon, M. Dumoulin, A. Matagne, L. Wyns, S. Muyldermans, and K. Conrath, "Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.", J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
Revets, H., P. De Baetselier, and S. Muyldermans, "Nanobodies as novel agents for cancer therapy.", Expert Opin Biol Ther, vol. 5, issue 1, pp. 111-24, 2005 Jan.
Huang, L., G. Reekmans, D. Saerens, J-M. Friedt, F. Frederix, L. Francis, S. Muyldermans, A. Campitelli, and C. Van Hoof, "Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays.", Biosens Bioelectron, vol. 21, issue 3, pp. 483-90, 2005 Sep 15.
Dumoulin, M., D. Canet, A. M. Last, E. Pardon, D. B. Archer, S. Muyldermans, L. Wyns, A. Matagne, C. V. Robinson, C. Redfield, et al., "Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.", J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
De Genst, E., K. Silence, M. Arbabi Ghahroudi, K. Decanniere, R. Loris, J. Kinne, L. Wyns, and S. Muyldermans, "Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.", J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
2004
De Genst, E., F. Handelberg, A. Van Meirhaeghe, S. Vynck, R. Loris, L. Wyns, and S. Muyldermans, "Chemical basis for the affinity maturation of a camel single domain antibody.", J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
Cortez-Retamozo, V., N. Backmann, P. D. Senter, U. Wernery, P. De Baetselier, S. Muyldermans, and H. Revets, "Efficient cancer therapy with a nanobody-based conjugate.", Cancer Res, vol. 64, issue 8, pp. 2853-7, 2004 Apr 15.
Stijlemans, B., K. Conrath, V. Cortez-Retamozo, H. Van Xong, L. Wyns, P. Senter, H. Revets, P. De Baetselier, S. Muyldermans, and S. Magez, "Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.", J Biol Chem, vol. 279, issue 2, pp. 1256-61, 2004 Jan 9.
Saerens, D., J. Kinne, E. Bosmans, U. Wernery, S. Muyldermans, and K. Conrath, "Single domain antibodies derived from dromedary lymph node and peripheral blood lymphocytes sensing conformational variants of prostate-specific antigen.", J Biol Chem, vol. 279, issue 50, pp. 51965-72, 2004 Dec 10.
Pleschberger, M., D. Saerens, S. Weigert, U. B. Sleytr, S. Muyldermans, M. Sára, and E. M. Egelseer, "An S-layer heavy chain camel antibody fusion protein for generation of a nanopatterned sensing layer to detect the prostate-specific antigen by surface plasmon resonance technology.", Bioconjug Chem, vol. 15, issue 3, pp. 664-71, 2004 May-Jun.
2003
Dumoulin, M., A. M. Last, A. Desmyter, K. Decanniere, D. Canet, G. Larsson, A. Spencer, D. B. Archer, J. Sasse, S. Muyldermans, et al., "A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.", Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
Loris, R., I. Marianovsky, J. Lah, T. Laeremans, H. Engelberg-Kulka, G. Glaser, S. Muyldermans, and L. Wyns, "Crystal structure of the intrinsically flexible addiction antidote MazE.", J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.
Conrath, K. E., U. Wernery, S. Muyldermans, and V. K. Nguyen, "Emergence and evolution of functional heavy-chain antibodies in Camelidae.", Dev Comp Immunol, vol. 27, issue 2, pp. 87-103, 2003 Feb.
Pleschberger, M., A. Neubauer, E. M. Egelseer, S. Weigert, B. Lindner, U. B. Sleytr, S. Muyldermans, and M. Sára, "Generation of a functional monomolecular protein lattice consisting of an s-layer fusion protein comprising the variable domain of a camel heavy chain antibody.", Bioconjug Chem, vol. 14, issue 2, pp. 440-8, 2003 Mar-Apr.
Nguyen, V. Khong, X. Zou, M. Lauwereys, L. Brys, M. Brüggemann, and S. Muyldermans, "Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells.", Immunology, vol. 109, issue 1, pp. 93-101, 2003 May.
2002
Cortez-Retamozo, V., M. Lauwereys, G. Hassanzade Gh, M. Gobert, K. Conrath, S. Muyldermans, P. De Baetselier, and H. Revets, "Efficient tumor targeting by single-domain antibody fragments of camels.", Int J Cancer, vol. 98, issue 3, pp. 456-62, 2002 Mar 20.
Nguyen, V. Khong, C. Su, S. Muyldermans, and W. van der Loo, "Heavy-chain antibodies in Camelidae; a case of evolutionary innovation.", Immunogenetics, vol. 54, issue 1, pp. 39-47, 2002 Apr.
De Genst, E., D. Areskoug, K. Decanniere, S. Muyldermans, and K. Andersson, "Kinetic and affinity predictions of a protein-protein interaction using multivariate experimental design.", J Biol Chem, vol. 277, issue 33, pp. 29897-907, 2002 Aug 16.
Dumoulin, M., K. Conrath, A. Van Meirhaeghe, F. Meersman, K. Heremans, L. G. J. Frenken, S. Muyldermans, L. Wyns, and A. Matagne, "Single-domain antibody fragments with high conformational stability.", Protein Sci, vol. 11, issue 3, pp. 500-15, 2002 Mar.
Desmyter, A., S. Spinelli, F. Payan, M. Lauwereys, L. Wyns, S. Muyldermans, and C. Cambillau, "Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.", J Biol Chem, vol. 277, issue 26, pp. 23645-50, 2002 Jun 28.
2001
Desmyter, A., K. Decanniere, S. Muyldermans, and L. Wyns, "Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody.", J Biol Chem, vol. 276, issue 28, pp. 26285-90, 2001 Jul 13.
Conrath, K. E., M. Lauwereys, M. Galleni, A. Matagne, J. M. Frère, J. Kinne, L. Wyns, and S. Muyldermans, "Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae.", Antimicrob Agents Chemother, vol. 45, issue 10, pp. 2807-12, 2001 Oct.

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