Publications
Found 24 results
Filters: Keyword is Models, Molecular and Author is S Muyldermans [Clear All Filters]
"Development of Cys38 knock-out and humanized version of NbAahII10 nanobody with improved neutralization of AahII scorpion toxin.",
Protein Eng Des Sel, vol. 24, issue 9, pp. 727-35, 2011 Sep.
"High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.",
PLoS Pathog, vol. 7, issue 6, pp. e1002072, 2011 Jun.
"Modulation of protein properties in living cells using nanobodies.",
Nat Struct Mol Biol, vol. 17, issue 1, pp. 133-8, 2010 Jan.
"Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase.",
Protein Sci, vol. 18, issue 3, pp. 619-28, 2009 Mar.
"General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.",
J Biol Chem, vol. 284, issue 5, pp. 3273-84, 2009 Jan 30.
"Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains.",
J Mol Biol, vol. 377, issue 2, pp. 478-88, 2008 Mar 21.
"A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry.",
Chemistry, vol. 12, issue 7, pp. 1915-23, 2006 Feb 20.
"Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH.",
J Mol Biol, vol. 350, issue 1, pp. 112-25, 2005 Jul 1.
"Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.",
J Mol Biol, vol. 352, issue 3, pp. 597-607, 2005 Sep 23.
"Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.",
J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
"Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.",
J Biol Chem, vol. 280, issue 14, pp. 14114-21, 2005 Apr 8.
"Chemical basis for the affinity maturation of a camel single domain antibody.",
J Biol Chem, vol. 279, issue 51, pp. 53593-601, 2004 Dec 17.
"A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.",
Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
"Crystal structure of the intrinsically flexible addiction antidote MazE.",
J Biol Chem, vol. 278, issue 30, pp. 28252-7, 2003 Jul 25.
"Kinetic and affinity predictions of a protein-protein interaction using multivariate experimental design.",
J Biol Chem, vol. 277, issue 33, pp. 29897-907, 2002 Aug 16.
"Degenerate interfaces in antigen-antibody complexes.",
J Mol Biol, vol. 313, issue 3, pp. 473-8, 2001 Oct 26.
"Functional heavy-chain antibodies in Camelidae.",
Adv Immunol, vol. 79, pp. 261-96, 2001.
"Single domain camel antibodies: current status.",
J Biotechnol, vol. 74, issue 4, pp. 277-302, 2001 Jun.
"Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?",
J Mol Biol, vol. 300, issue 1, pp. 83-91, 2000 Jun 30.
"The crystal structure of recombinant rat pancreatic RNase A.",
Proteins, vol. 35, issue 1, pp. 1-12, 1999 Apr 1.
"A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.",
Structure, vol. 7, issue 4, pp. 361-70, 1999 Apr 15.
"Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies.",
J Mol Recognit, vol. 12, issue 2, pp. 131-40, 1999 Mar-Apr.
"Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate.",
Proteins, vol. 32, issue 4, pp. 515-22, 1998 Sep 1.
"Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5.",
Biochemistry, vol. 33, issue 37, pp. 11079-86, 1994 Sep 20.