Publications

Found 6 results
Filters: Author is Barlow, John N  [Clear All Filters]
2014
Oyen, D., J. Steyaert, and J. N. Barlow, "Inhibition of ligand exchange kinetics via active-site trapping with an antibody fragment.", Biochemistry, vol. 53, issue 12, pp. 1879-81, 2014 Apr 01.
2013
Oyen, D., R. Wechselberger, V. Srinivasan, J. Steyaert, and J. N. Barlow, "Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.", Biochim Biophys Acta, vol. 1834, issue 10, pp. 2147-57, 2013 Oct.
2011
Oyen, D., V. Srinivasan, J. Steyaert, and J. N. Barlow, "Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.", J Mol Biol, vol. 407, issue 1, pp. 138-48, 2011 Mar 18.
2009
Barlow, J. N., K. Conrath, and J. Steyaert, "Substrate-dependent modulation of enzyme activity by allosteric effector antibodies.", Biochim Biophys Acta, vol. 1794, issue 8, pp. 1259-68, 2009 Aug.
2007
Barlow, J. N., and J. Steyaert, "Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax.", Biochim Biophys Acta, vol. 1774, issue 11, pp. 1451-61, 2007 Nov.
2006
Vandemeulebroucke, A., W. Versées, J. Steyaert, and J. N. Barlow, "Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.", Biochemistry, vol. 45, issue 30, pp. 9307-18, 2006 Aug 01.