Publications
Found 19 results
Filters: Author is Christopher M Dobson [Clear All Filters]
"Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.",
J Mol Biol, vol. 425, issue 14, pp. 2397-411, 2013 Jul 24.
"A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.",
J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
"Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.",
J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
"Characterization of folding the four-helix bundle protein Rop by real-time NMR.",
Protein Eng Des Sel, vol. 21, issue 3, pp. 165-70, 2008 Mar.
"Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.",
Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
"Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.",
J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
"A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.",
Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
"Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: evidence for local rearrangements during folding from high concentrations of denaturant.",
Biochemistry, vol. 42, issue 17, pp. 4883-95, 2003 May 6.
"Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments.",
J Mol Biol, vol. 330, issue 2, pp. 397-407, 2003 Jul 4.
"A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding.",
Protein Sci, vol. 10, issue 6, pp. 1216-24, 2001 Jun.
"Development of enzymatic activity during protein folding. Detection of a spectroscopically silent native-like intermediate of muscle acylphosphatase.",
J Biol Chem, vol. 274, issue 29, pp. 20151-8, 1999 Jul 16.
"Conformational stability of muscle acylphosphatase: the role of temperature, denaturant concentration, and pH.",
Biochemistry, vol. 37, issue 5, pp. 1447-55, 1998 Feb 3.
"Real-time NMR studies of protein folding",
Acc. Chem. Res., vol. 31, pp. 773-780, 1998.
"Slow cooperative folding of a small globular protein HPr.",
Biochemistry, vol. 37, issue 2, pp. 622-37, 1998 Jan 13.
"Slow folding of muscle acylphosphatase in the absence of intermediates.",
J Mol Biol, vol. 283, issue 4, pp. 883-91, 1998 Nov 6.
"Structural characterization of the transition state for folding of muscle acylphosphatase.",
J Mol Biol, vol. 283, issue 4, pp. 893-903, 1998 Nov 6.
"Detection of residue contacts in a protein folding intermediate.",
Proc Natl Acad Sci U S A, vol. 94, issue 14, pp. 7182-5, 1997 Jul 8.
"Protein folding monitored at individual residues during a two-dimensional NMR experiment.",
Science, vol. 274, issue 5290, pp. 1161-3, 1996 Nov 15.
"Following protein folding in real time using NMR spectroscopy.",
Nat Struct Biol, vol. 2, issue 10, pp. 865-70, 1995 Oct.