Publications

Found 19 results
Filters: Author is Christopher M Dobson  [Clear All Filters]
2013
Guilliams, T., F. El-Turk, A. K. Buell, E. M. O'Day, F. A. Aprile, E. K. Esbjörner, M. Vendruscolo, N. Cremades, E. Pardon, L. Wyns, et al., "Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages.", J Mol Biol, vol. 425, issue 14, pp. 2397-411, 2013 Jul 24.
De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.
2010
De Genst, E., T. Guilliams, J. Wellens, E. M. O'Day, C. A. Waudby, S. Meehan, M. Dumoulin, S-T. D. Hsu, N. Cremades, K. H. G. Verschueren, et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2008
van Nuland, N. A. J., C. M. Dobson, and L. Regan, "Characterization of folding the four-helix bundle protein Rop by real-time NMR.", Protein Eng Des Sel, vol. 21, issue 3, pp. 165-70, 2008 Mar.
Chan, P-H., E. Pardon, L. Menzer, E. De Genst, J. R. Kumita, J. Christodoulou, D. Saerens, A. Brans, F. Bouillenne, D. B. Archer, et al., "Engineering a camelid antibody fragment that binds to the active site of human lysozyme and inhibits its conversion into amyloid fibrils.", Biochemistry, vol. 47, issue 42, pp. 11041-54, 2008 Oct 21.
2005
Dumoulin, M., D. Canet, A. M. Last, E. Pardon, D. B. Archer, S. Muyldermans, L. Wyns, A. Matagne, C. V. Robinson, C. Redfield, et al., "Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations.", J Mol Biol, vol. 346, issue 3, pp. 773-88, 2005 Feb 25.
2003
Dumoulin, M., A. M. Last, A. Desmyter, K. Decanniere, D. Canet, G. Larsson, A. Spencer, D. B. Archer, J. Sasse, S. Muyldermans, et al., "A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.", Nature, vol. 424, issue 6950, pp. 783-8, 2003 Aug 14.
Azuaga, A. I., D. Canet, G. Smeenk, R. Berends, F. Titgemeijer, R. Duurkens, P. L. Mateo, R. M. Scheek, G. T. Robillard, C. M. Dobson, et al., "Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: evidence for local rearrangements during folding from high concentrations of denaturant.", Biochemistry, vol. 42, issue 17, pp. 4883-95, 2003 May 6.
Canet, D., C. E. Lyon, R. M. Scheek, G. T. Robillard, C. M. Dobson, P. J. Hore, and N. A. J. van Nuland, "Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments.", J Mol Biol, vol. 330, issue 2, pp. 397-407, 2003 Jul 4.
2001
Reader, J. S., N. A. J. van Nuland, G. S. Thompson, S. J. Ferguson, C. M. Dobson, and S. E. Radford, "A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding.", Protein Sci, vol. 10, issue 6, pp. 1216-24, 2001 Jun.
1999
Chiti, F., N. Taddei, E. Giannoni, N. A. J. van Nuland, G. Ramponi, and C. M. Dobson, "Development of enzymatic activity during protein folding. Detection of a spectroscopically silent native-like intermediate of muscle acylphosphatase.", J Biol Chem, vol. 274, issue 29, pp. 20151-8, 1999 Jul 16.
1998
Chiti, F., N. A. J. van Nuland, N. Taddei, F. Magherini, M. Stefani, G. Ramponi, and C. M. Dobson, "Conformational stability of muscle acylphosphatase: the role of temperature, denaturant concentration, and pH.", Biochemistry, vol. 37, issue 5, pp. 1447-55, 1998 Feb 3.
van Nuland, N. A. J., V.. Forge, J.. Balbach, and C. M. Dobson, "Real-time NMR studies of protein folding", Acc. Chem. Res., vol. 31, pp. 773-780, 1998.
van Nuland, N. A. J., W. Meijberg, J. Warner, V. Forge, R. M. Scheek, G. T. Robillard, and C. M. Dobson, "Slow cooperative folding of a small globular protein HPr.", Biochemistry, vol. 37, issue 2, pp. 622-37, 1998 Jan 13.
van Nuland, N. A. J., F. Chiti, N. Taddei, G. Raugei, G. Ramponi, and C. M. Dobson, "Slow folding of muscle acylphosphatase in the absence of intermediates.", J Mol Biol, vol. 283, issue 4, pp. 883-91, 1998 Nov 6.
Chiti, F., N. Taddei, N. A. J. van Nuland, F. Magherini, M. Stefani, G. Ramponi, and C. M. Dobson, "Structural characterization of the transition state for folding of muscle acylphosphatase.", J Mol Biol, vol. 283, issue 4, pp. 893-903, 1998 Nov 6.
1997
Balbach, J., V. Forge, W. S. Lau, J. A. Jones, N. A. J. van Nuland, and C. M. Dobson, "Detection of residue contacts in a protein folding intermediate.", Proc Natl Acad Sci U S A, vol. 94, issue 14, pp. 7182-5, 1997 Jul 8.
1996
Balbach, J., V. Forge, W. S. Lau, N. A. J. van Nuland, K. Brew, and C. M. Dobson, "Protein folding monitored at individual residues during a two-dimensional NMR experiment.", Science, vol. 274, issue 5290, pp. 1161-3, 1996 Nov 15.
1995
Balbach, J., V. Forge, N. A. J. van Nuland, S. L. Winder, P. J. Hore, and C. M. Dobson, "Following protein folding in real time using NMR spectroscopy.", Nat Struct Biol, vol. 2, issue 10, pp. 865-70, 1995 Oct.