Principles of structures of animal and plant lectins.

TitlePrinciples of structures of animal and plant lectins.
Publication TypeJournal Article
Year of Publication2002
AuthorsLoris, R.
JournalBiochim Biophys Acta
Volume1572
Issue2-3
Pagination198-208
Date Published2002 Sep 19
ISSN0006-3002
KeywordsAnimals, Binding Sites, Carbohydrates, Evolution, Molecular, Humans, Lectins, Models, Molecular, Molecular Conformation, Molecular Structure, Plant Lectins, Plants, Protein Binding
Abstract

Lectins form a diverse group of protein families that have in common their ability to specifically recognize certain carbohydrates. Crystal structures of members of the different animal and plant lectin families have revealed a wide variety of lectin folds and carbohydrate binding site architectures. Despite this large variability, a number of interesting cases of convergent as well as divergent evolution among animal and plant lectin families can be noted. These similarities exist at the levels of the protein fold, the architecture of the binding site as well as quaternary structure and may be derived from similar functional needs.

Alternate JournalBiochim. Biophys. Acta
PubMed ID12223270