Title | Recommendations of the wwPDB NMR Validation Task Force. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Montelione, G. T., M. Nilges, A. Bax, P. Güntert, T. Herrmann, J. S. Richardson, C. D. Schwieters, W. F. Vranken, G. W. Vuister, D. S. Wishart, H. M. Berman, G. J. Kleywegt, and J. L. Markley |
Journal | Structure |
Volume | 21 |
Issue | 9 |
Pagination | 1563-70 |
Date Published | 2013 Sep 3 |
ISSN | 1878-4186 |
Keywords | Advisory Committees, Databases, Protein, Guidelines as Topic, Knowledge Bases, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Protein Conformation, Proteins, Quality Control, Reference Standards, Validation Studies as Topic |
Abstract | As methods for analysis of biomolecular structure and dynamics using nuclear magnetic resonance spectroscopy (NMR) continue to advance, the resulting 3D structures, chemical shifts, and other NMR data are broadly impacting biology, chemistry, and medicine. Structure model assessment is a critical area of NMR methods development, and is an essential component of the process of making these structures accessible and useful to the wider scientific community. For these reasons, the Worldwide Protein Data Bank (wwPDB) has convened an NMR Validation Task Force (NMR-VTF) to work with wwPDB partners in developing metrics and policies for biomolecular NMR data harvesting, structure representation, and structure quality assessment. This paper summarizes the recommendations of the NMR-VTF, and lays the groundwork for future work in developing standards and metrics for biomolecular NMR structure quality assessment. |
DOI | 10.1016/j.str.2013.07.021 |
Alternate Journal | Structure |
PubMed ID | 24010715 |
PubMed Central ID | PMC3884077 |
Grant List | 075968 / / Wellcome Trust / United Kingdom 088944 / / Wellcome Trust / United Kingdom BB/E007511/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom BB/J007471/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom BB/J007897/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom BB/K021249/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom P41 GM103399 / GM / NIGMS NIH HHS / United States P41 LM005799 / LM / NLM NIH HHS / United States P41 LM05799 / LM / NLM NIH HHS / United States R01 GM073930 / GM / NIGMS NIH HHS / United States R01-GM073930 / GM / NIGMS NIH HHS / United States U54 GM094597 / GM / NIGMS NIH HHS / United States U54 GM094597 / GM / NIGMS NIH HHS / United States |
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