EUROCarbDB: An open-access platform for glycoinformatics.

TitleEUROCarbDB: An open-access platform for glycoinformatics.
Publication TypeJournal Article
Year of Publication2011
Authorsvon der Lieth, C-W., A. Ardá Freire, D. Blank, M. P. Campbell, A. Ceroni, D. R. Damerell, A. Dell, R. A. Dwek, B. Ernst, R. Fogh, M. Frank, H. Geyer, R. Geyer, M. J. Harrison, K. Henrick, S. Herget, W. E. Hull, J. Ionides, H. J. Joshi, J. P. Kamerling, B. R. Leeflang, T. Lütteke, M. Lundborg, K. Maass, A. Merry, R. Ranzinger, J. Rosen, L. Royle, P. M. Rudd, S. Schloissnig, R. Stenutz, W. F. Vranken, G. Widmalm, and S. M. Haslam
JournalGlycobiology
Volume21
Issue4
Pagination493-502
Date Published2011 Apr
ISSN1460-2423
KeywordsAnimals, Carbohydrate Conformation, Carbohydrates, Computational Biology, Databases as Topic, Glycomics, Humans, Models, Molecular, Molecular Weight, Online Systems, Software
Abstract

The EUROCarbDB project is a design study for a technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology and glycomic research. EUROCarbDB is a relational database containing glycan structures, their biological context and, when available, primary and interpreted analytical data from high-performance liquid chromatography, mass spectrometry and nuclear magnetic resonance experiments. Database content can be accessed via a web-based user interface. The database is complemented by a suite of glycoinformatics tools, specifically designed to assist the elucidation and submission of glycan structure and experimental data when used in conjunction with contemporary carbohydrate research workflows. All software tools and source code are licensed under the terms of the Lesser General Public License, and publicly contributed structures and data are freely accessible. The public test version of the web interface to the EUROCarbDB can be found at http://www.ebi.ac.uk/eurocarb.

DOI10.1093/glycob/cwq188
Alternate JournalGlycobiology
PubMed ID21106561
PubMed Central IDPMC3055595
Grant ListB20259 / / Biotechnology and Biological Sciences Research Council / United Kingdom
BB/E005071/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom
BB/H004130/1 / / Biotechnology and Biological Sciences Research Council / United Kingdom
BBF0083091 / / Biotechnology and Biological Sciences Research Council / United Kingdom
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