It takes two to rule translation elongation.

TitleIt takes two to rule translation elongation.
Publication TypeJournal Article
Year of Publication2015
AuthorsVersées, W.
JournalStructure
Volume23
Issue1
Pagination7-9
Date Published2015 Jan 06
ISSN1878-4186
KeywordsPeptide Elongation Factor 2, Repressor Proteins, RNA, Transfer, Saccharomyces cerevisiae Proteins
Abstract

In this issue of Structure, Glatt and colleagues report the structure of the Kti11/Kti13 heterodimer. This study reveals how dimerization and Fe(2+) binding are required for modification of both tRNA and EF2, thus suggesting a mechanism for regulation of translation elongation via two different pathways.

DOI10.1016/j.str.2014.12.007
Alternate JournalStructure
PubMed ID25565102
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