Title | SnapShot: Intrinsic Structural Disorder. |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Guharoy, M., K. Pauwels, and P. Tompa |
Journal | Cell |
Volume | 161 |
Issue | 5 |
Pagination | 1230-1230.e1 |
Date Published | 2015 May 21 |
ISSN | 1097-4172 |
Keywords | Animals, Humans, Protein Conformation, Protein Unfolding, Proteins |
Abstract | Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured; rather, intrinsic structural disorder is their native, functional state. |
DOI | 10.1016/j.cell.2015.05.024 |
Alternate Journal | Cell |
PubMed ID | 26000490 |
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