SnapShot: Intrinsic Structural Disorder.

TitleSnapShot: Intrinsic Structural Disorder.
Publication TypeJournal Article
Year of Publication2015
AuthorsGuharoy, M., Pauwels K., and Tompa P.
JournalCell
Volume161
Issue5
Pagination1230-1230.e1
Date Published2015 May 21
ISSN1097-4172
KeywordsAnimals, Humans, Protein Conformation, Protein Unfolding, Proteins
Abstract

Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured; rather, intrinsic structural disorder is their native, functional state.

DOI10.1016/j.cell.2015.05.024
Alternate JournalCell
PubMed ID26000490
Research group: