Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria.

TitleArchitectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria.
Publication TypeJournal Article
Year of Publication2008
AuthorsFronzes, R., Remaut H., and Waksman G.
JournalEMBO J
Volume27
Issue17
Pagination2271-80
Date Published2008 Sep 3
Type of Articlesmm
ISSN0261-4189
KeywordsBacterial Proteins, Fimbriae Proteins, Fimbriae, Bacterial, Gram-Negative Bacteria, Models, Molecular, Multiprotein Complexes
Abstract

Bacteria commonly expose non-flagellar proteinaceous appendages on their outer surfaces. These extracellular structures, called pill or fimbriae, are employed in attachment and invasion, biofilm formation, cell motility or protein and DNA transport across membranes. Over the past 15 years, the power of molecular and structural techniques has revolutionalized our understanding of the biogenesis, structure, function and mode of action of these bacterial organelles. Here, we review the five known classes of Gram-negative non-flagellar appendages from a biosynthetic and structural point of view.

DOI10.1038/emboj.2008.155
Alternate JournalEMBO J.
PubMed ID18668121
PubMed Central IDPMC2500206
Research group: