Multi-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics.

TitleMulti-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics.
Publication TypeJournal Article
Year of Publication2012
AuthorsSalmon, L., L. Pierce, A. Grimm, J. L. Ortega Roldan, L. Mollica, M. Ringkjøbing Jensen, N. A. J. van Nuland, P. R. L. Markwick, A. J McCammon, and M. Blackledge
JournalAngew Chem Int Ed Engl
Volume51
Issue25
Pagination6103-6
Date Published2012 Jun 18
ISSN1521-3773
KeywordsAdaptor Proteins, Signal Transducing, Cytoskeletal Proteins, Magnetic Resonance Spectroscopy, Molecular Dynamics Simulation, Proteins, src Homology Domains
DOI10.1002/anie.201202026
Alternate JournalAngew. Chem. Int. Ed. Engl.
PubMed ID22565613
PubMed Central IDPMC3541011
Grant ListP41 GM103426 / GM / NIGMS NIH HHS / United States
R01 GM031749 / GM / NIGMS NIH HHS / United States
/ / Howard Hughes Medical Institute / United States