|Title||GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks.|
|Publication Type||Journal Article|
|Year of Publication||2006|
|Authors||Vlasblom, J., S. Wu, S. Pu, M. Superina, G. Liu, C. Orsi, and S. J. Wodak|
|Date Published||2006 Sep 1|
|Keywords||Algorithms, Computer Graphics, Computer Simulation, Computing Methodologies, Gene Expression Profiling, Models, Biological, Oligonucleotide Array Sequence Analysis, Protein Interaction Mapping, Proteome, Signal Transduction, Software, User-Computer Interface|
MOTIVATION: Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community.RESULTS: We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules.AVAILABILITY: The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca.