Identification of predictive sequence motifs limited by protein structure data base size.

TitleIdentification of predictive sequence motifs limited by protein structure data base size.
Publication TypeJournal Article
Year of Publication1988
AuthorsRooman, M. J., and Wodak S. J.
JournalNature
Volume335
Issue6185
Pagination45-9
Date Published1988 Sep 1
ISSN0028-0836
KeywordsAmino Acid Sequence, Information Systems, Protein Conformation
Abstract

Associations between short amino acid sequence patterns and protein secondary structure classes can be found by searching a data base of known protein structures. Analysis of these associations suggests that secondary structure of proteins can be determined locally by sequence motifs of high predictive value, but at present our ability to find these motifs is limited by the size of the available data bases.

DOI10.1038/335045a0
Alternate JournalNature
PubMed ID3412459