SteyaertGroup

Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.

Wohlkonig, A., H. Remaut, M. Moune, A. Tanina, F. Meyer, M. Desroses, J. Steyaert, N. Willand, A. R. Baulard, and R. Wintjens, "Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.", Biochem Biophys Res Commun, vol. 487, issue 2, pp. 403-408, 2017 05 27.

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.

Cahill, T. J., A. R. B. Thomsen, J. T. Tarrasch, B. Plouffe, A. H. Nguyen, F. Yang, L-Y. Huang, A. W. Kahsai, D. L. Bassoni, B. J. Gavino, et al., "Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.", Proc Natl Acad Sci U S A, vol. 114, issue 10, pp. 2562-2567, 2017 Mar 07.

Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.

Perez, C., M. Köhler, D. Janser, E. Pardon, J. Steyaert, R. Zenobi, and K. P. Locher, "Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.", Sci Rep, vol. 7, pp. 46641, 2017 Apr 19.

Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.

Barros-Álvarez, X., K. M. Kerchner, C. Yeow Koh, S. Turley, E. Pardon, J. Steyaert, R. M. Ranade, R. J Gillespie, Z. Zhang, C. L. M. J. Verlinde, et al., "Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts.", Biochimie, vol. 138, pp. 124-136, 2017 Jul.

A specific nanobody prevents amyloidogenesis of D76N β-microglobulin in vitro and modifies its tissue distribution in vivo.

Raimondi, S., R. Porcari, P. P Mangione, G. Verona, J. Marcoux, S. Giorgetti, G. W. Taylor, S. Ellmerich, M. Ballico, S. Zanini, et al., "A specific nanobody prevents amyloidogenesis of D76N β-microglobulin in vitro and modifies its tissue distribution in vivo.", Sci Rep, vol. 7, pp. 46711, 2017 Apr 21.

Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased β Adrenergic Receptor Ligands.

Martin, C., S. L. C. Moors, M. Danielsen, C. Betti, C. Fabris, D. Sejer Pedersen, E. Pardon, M. Peyressatre, K. Fehér, J. C. Martins, et al., "Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased β Adrenergic Receptor Ligands.", Chemistry, vol. 23, issue 40, pp. 9632-9640, 2017 Jul 18.

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.

Ayoub, M. Akli, P. Crépieux, M. Koglin, M. Parmentier, J-P. Pin, A. Poupon, E. Reiter, M. Smit, J. Steyaert, H. Watier, et al., "Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.", MAbs, vol. 9, issue 5, pp. 735-741, 2017 07.

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