tRNA

N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.

Goeminne, A., M. Berg, M. McNaughton, G. Bal, G. Surpateanu, P. Van der Veken, S. De Prol, W. Versées, J. Steyaert, A. Haemers, et al., "N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.", Bioorg Med Chem, vol. 16, issue 14, pp. 6752-63, 2008 Jul 15.

Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.

Berg, M., G. Bal, A. Goeminne, P. Van der Veken, W. Versées, J. Steyaert, A. Haemers, and K. Augustyns, "Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.", ChemMedChem, vol. 4, issue 2, pp. 249-60, 2009 Feb.

Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.

Versées, W., A. Goeminne, M. Berg, A. Vandemeulebroucke, A. Haemers, K. Augustyns, and J. Steyaert, "Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.", Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.

Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.

De Vocht, C., A. Ranquin, R. Willaert, J. A. Van Ginderachter, T. Vanhaecke, V. Rogiers, W. Versées, P. Van Gelder, and J. Steyaert, "Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.", J Control Release, vol. 137, issue 3, pp. 246-54, 2009 Aug 04.

Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.

Loverix, S., P. Geerlings, M. McNaughton, K. Augustyns, A. Vandemeulebroucke, J. Steyaert, and W. Versées, "Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage.", J Biol Chem, vol. 280, issue 15, pp. 14799-802, 2005 Apr 15.

Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system.

Ranquin, A., W. Versées, W. Meier, J. Steyaert, and P. Van Gelder, "Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system.", Nano Lett, vol. 5, issue 11, pp. 2220-4, 2005 Nov.

New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product.

Muzzolini, L., W. Versées, P. Tornaghi, E. Van Holsbeke, J. Steyaert, and M. Degano, "New insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product.", Biochemistry, vol. 45, issue 3, pp. 773-82, 2006 Jan 24.

Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.

Vandemeulebroucke, A., W. Versées, J. Steyaert, and J. N. Barlow, "Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.", Biochemistry, vol. 45, issue 30, pp. 9307-18, 2006 Aug 01.

The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.

Versées, W., S. Spaepen, J. Vanderleyden, and J. Steyaert, "The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.", FEBS J, vol. 274, issue 9, pp. 2363-75, 2007 May.

Characterization of phenylpyruvate decarboxylase, involved in auxin production of Azospirillum brasilense.

Spaepen, S., W. Versées, D. Gocke, M. Pohl, J. Steyaert, and J. Vanderleyden, "Characterization of phenylpyruvate decarboxylase, involved in auxin production of Azospirillum brasilense.", J Bacteriol, vol. 189, issue 21, pp. 7626-33, 2007 Nov.

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