Nanobodies

Nanobody production and applications

Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target.

De Vos, J., N. Devoogdt, T. Lahoutte, and S. Muyldermans, "Camelid single-domain antibody-fragment engineering for (pre)clinical in vivo molecular imaging applications: adjusting the bullet to its target.", Expert Opin Biol Ther, vol. 13, issue 8, pp. 1149-60, 2013 Aug.

A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.

De Genst, E., P-H. Chan, E. Pardon, S-T. D. Hsu, J. R. Kumita, J. Christodoulou, L. Menzer, D. Y. Chirgadze, C. V. Robinson, S. Muyldermans, et al., "A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.", J Phys Chem B, vol. 117, issue 42, pp. 13245-58, 2013 Oct 24.

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