LorisGroup

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.

Talavera, A., J. Hendrix, W. Versées, D. Jurenas, K. Van Nerom, N. Vandenberk, R. Kumar Singh, A. Konijnenberg, S. De Gieter, D. Castro-Roa, et al., "Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.", Sci Adv, vol. 4, issue 3, pp. eaap9714, 2018 Mar.

Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.

Hadži, S., A. Garcia-Pino, S. Haesaerts, D. Jurenas, K. Gerdes, J. Lah, and R. Loris, "Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a β-strand sliding mechanism.", Nucleic Acids Res, vol. 45, issue 8, pp. 4972-4983, 2017 May 05.

Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.

Talavera, A., H. Tamman, A. Ainelo, S. Hadǽi, A. Garcia-Pino, R. Hõrak, A. Konijnenberg, and R. Loris, "Production, biophysical characterization and crystallization of Pseudomonas putida GraA and its complexes with GraT and the graTA operator.", Acta Crystallogr F Struct Biol Commun, vol. 73, issue Pt 8, pp. 455-462, 2017 Aug 01.

Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.

Beirnaert, E., A. Desmyter, S. Spinelli, M. Lauwereys, L. Aarden, T. Dreier, R. Loris, K. Silence, C. Pollet, C. Cambillau, et al., "Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.", Front Immunol, vol. 8, pp. 867, 2017.

A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.

Sterckx, Y. G. - J., T. Jové, A. V. Shkumatov, A. Garcia-Pino, L. Geerts, M. De Kerpel, J. Lah, H. De Greve, L. Van Melderen, and R. Loris, "A unique hetero-hexadecameric architecture displayed by the Escherichia coli O157 PaaA2-ParE2 antitoxin-toxin complex.", J Mol Biol, vol. 428, issue 8, pp. 1589-603, 2016 Apr 24.

Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.

Blanchetot, C., N. De Jonge, A. Desmyter, N. Ongenae, E. Hofman, A. Klarenbeek, A. Sadi, A. Hultberg, A. Kretz-Rommel, S. Spinelli, et al., "Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.", J Biol Chem, vol. 291, issue 26, pp. 13846-54, 2016 Jun 24.

Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.

Egea-Jimenez, A. Luis, R. Gallardo, A. Garcia-Pino, Y. Ivarsson, A. Maria Wawrzyniak, R. Kashyap, R. Loris, J. Schymkowitz, F. Rousseau, and P. Zimmermann, "Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling.", Nat Commun, vol. 7, pp. 12101, 2016 07 08.

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