Jan Steyaert

Primary tabs

2010
Abskharon, R. N. N., Soror S. H., Pardon E., Hassan H. El, Legname G., Steyaert J., and Wohlkonig A., "Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein.", Acta Crystallogr Sect F Struct Biol Cryst Commun, vol. 66, issue Pt 12, pp. 1644-6, 2010 Dec 1.
Berg, M., Kohl L., Van der Veken P., Joossens J., Al-Salabi M. I., Castagna V., Giannese F., Cos P., Versées W., Steyaert J., et al., "Evaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis.", Antimicrob Agents Chemother, vol. 54, issue 5, pp. 1900-8, 2010 May.
Vercruysse, T., Pardon E., Vanstreels E., Steyaert J., and Daelemans D., "An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.", J Biol Chem, vol. 285, issue 28, pp. 21768-80, 2010 Jul 9.
Ryckaert, S., Pardon E., Steyaert J., and Callewaert N., "Isolation of antigen-binding camelid heavy chain antibody fragments (nanobodies) from an immune library displayed on the surface of Pichia pastoris.", J Biotechnol, vol. 145, issue 2, pp. 93-8, 2010 Jan 15.
Van den Abbeele, A., De Clercq S., De Ganck A., De Corte V., Van Loo B., Soror S. Hamdy, Srinivasan V., Steyaert J., Vandekerckhove J., and Gettemans J., "A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction.", Cell Mol Life Sci, vol. 67, issue 9, pp. 1519-35, 2010 May.
De Vocht, C., Ranquin A., Van Ginderachter J., Vanhaecke T., Rogiers V., Van Gelder P., Versées W., and Steyaert J., "Polymeric nanoreactors for enzyme replacement therapy of MNGIE.", J Control Release, vol. 148, issue 1, pp. e19-20, 2010 Nov 20.
Vandemeulebroucke, A., Minici C., Bruno I., Muzzolini L., Tornaghi P., Parkin D. W., Versées W., Steyaert J., and Degano M., "Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.", Biochemistry, vol. 49, issue 41, pp. 8999-9010, 2010 Oct 19.
De Genst, E., Guilliams T., Wellens J., O'Day E. M., Waudby C. A., Meehan S., Dumoulin M., Hsu S-T. D., Cremades N., Verschueren K. H. G., et al., "Structure and properties of a complex of α-synuclein and a single-domain camelid antibody.", J Mol Biol, vol. 402, issue 2, pp. 326-43, 2010 Sep 17.
2009
De Vocht, C., Ranquin A., Willaert R., Van Ginderachter J. A., Vanhaecke T., Rogiers V., Versées W., Van Gelder P., and Steyaert J., "Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE.", J Control Release, vol. 137, issue 3, pp. 246-54, 2009 Aug 4.
Korotkov, K. V., Pardon E., Steyaert J., and Hol W. G. J., "Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.", Structure, vol. 17, issue 2, pp. 255-65, 2009 Feb 13.
Versées, W., Goeminne A., Berg M., Vandemeulebroucke A., Haemers A., Augustyns K., and Steyaert J., "Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.", Biochim Biophys Acta, vol. 1794, issue 6, pp. 953-60, 2009 Jun.
Lam, A. Y., Pardon E., Korotkov K. V., Hol W. G. J., and Steyaert J., "Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.", J Struct Biol, vol. 166, issue 1, pp. 8-15, 2009 Apr.
Barlow, J. N., Conrath K., and Steyaert J., "Substrate-dependent modulation of enzyme activity by allosteric effector antibodies.", Biochim Biophys Acta, vol. 1794, issue 8, pp. 1259-68, 2009 Aug.
Berg, M., Bal G., Goeminne A., Van der Veken P., Versées W., Steyaert J., Haemers A., and Augustyns K., "Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors.", ChemMedChem, vol. 4, issue 2, pp. 249-60, 2009 Feb.

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