Jan Steyaert

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TypeTitleAuthorRepliesLast updated
BiblioN-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase. wversees02 months 3 weeks ago
BiblioA flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax. wversees02 months 3 weeks ago
BiblioMolecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. wversees02 months 3 weeks ago
BiblioCharacterization of phenylpyruvate decarboxylase, involved in auxin production of Azospirillum brasilense. wversees02 months 3 weeks ago
BiblioThe crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism. wversees02 months 3 weeks ago
BiblioMultiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. wversees02 months 3 weeks ago
BiblioNew insights into the mechanism of nucleoside hydrolases from the crystal structure of the Escherichia coli YbeK protein bound to the reaction product. wversees02 months 3 weeks ago
BiblioTherapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system. wversees02 months 3 weeks ago
BiblioSubstrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. wversees02 months 3 weeks ago
BiblioLeaving group activation by aromatic stacking: an alternative to general acid catalysis. wversees02 months 3 weeks ago
BiblioPre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. wversees02 months 3 weeks ago
BiblioCatalysis by nucleoside hydrolases. wversees02 months 3 weeks ago
BiblioCloning, preliminary characterization and crystallization of nucleoside hydrolases from Caenorhabditis elegans and Campylobacter jejuni. wversees02 months 3 weeks ago
BiblioEnzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. wversees02 months 3 weeks ago
BiblioCharacterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates. wversees02 months 3 weeks ago
BiblioStructure of an early native-like intermediate of β2-microglobulin amyloidogenesis. wversees02 months 3 weeks ago
BiblioStructure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei. wversees02 months 3 weeks ago
BiblioEvaluation of nucleoside hydrolase inhibitors for treatment of African trypanosomiasis. wversees02 months 3 weeks ago
BiblioAssessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE. wversees02 months 3 weeks ago
BiblioCrystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors. wversees02 months 3 weeks ago
BiblioSynthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors. wversees02 months 3 weeks ago
BiblioNanobodies to Study G Protein-Coupled Receptor Structure and Function. Jan Steyaert01 year 8 months ago
BiblioQuiescin-sulfhydryl oxidase inhibits prion formation . Jan Steyaert01 year 8 months ago
BiblioSortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities. Jan Steyaert01 year 8 months ago
BiblioInternalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes. Jan Steyaert01 year 8 months ago

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